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GPT-4o vs Claude Sonnet 4.5: optimized frontier API rates compared

GPT-4o is cheaper for low-cache workloads and output-heavy requests. Claude Sonnet 4.5 becomes cheaper when prompt caching is highly active.

Optimized premium intelligence confrontation.

GPT-4o and Claude Sonnet 4.5 represent premium, highly optimized intelligence. Their cost efficiency depends on how your app structures requests.

By TechCompare · Updated

Cost Comparison

Based on 100,000 input tokens (50% cached), 5,000 output tokens, and 100 requests.Prices are fetched live from OpenRouter and may include temporary promotional discounts not accounted for in our article and comparison figures.

Option A
GPT-4o
Wins 2 of 4 compared specs
Option B
Claude Sonnet 4.5
Wins 1 of 4 compared specs

Side-by-side specs

SpecGPT-4oClaude Sonnet 4.5
Input Cost (per M)
$2.50 (better on this spec)
$3.00
Output Cost (per M)
$10.00 (better on this spec)
$15.00
Cached Input (per M)
$1.25
$0.30 (better on this spec)
Batch Discount
50%
50%

How they differ

GPT-4o costs $2.50 per million input tokens and $10.00 per million output tokens, with a 50% caching discount. Claude Sonnet 4.5 costs $3.00 per million input tokens and $15.00 per million output tokens, with a 90% caching discount.

Verdict

GPT-4o wins the base rows: $2.50/M input against $3.00 and $10.00/M output against $15.00. Sonnet 4.5's lever is its 90% cache discount versus GPT-4o's 50%, dropping cached input to $0.30/M versus $1.25/M. The crossover sits near 50% prompt reuse. Below it, GPT-4o's lower bases hold. Above it, Sonnet's deeper cache overtakes. Batch ties at 50% on both, so it doesn't tilt the live-call math.

Which should you pick?

Choose GPT-4o

Standard low-cache requests, transactional text chat, and output-heavy tasks.

Choose Claude Sonnet 4.5

Document summarization, high-caching multi-turn chats, and agent frameworks.

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Frequently asked questions

When does Claude Sonnet 4.5 become cheaper than GPT-4o?
On workloads with heavy prompt caching. Sonnet 4.5's cached input is $0.30/M (90% discount) versus GPT-4o's $1.25/M (50% discount). Below roughly 50% reuse GPT-4o wins. Above 50% reuse with long shared system prompts, Sonnet 4.5's deeper discount erases its higher base price and reverses the verdict.
Which is cheaper for output-heavy workloads?
GPT-4o. At $10.00/M output it beats Sonnet 4.5's $15.00/M. For long-form generation, transcripts, or chat with verbose responses, GPT-4o's lower output price compounds. Sonnet 4.5's edge on cached input doesn't help when output dominates the bill.
How much does the 50% batch discount save on each model?
Both offer a 50% batch discount. In batch mode GPT-4o drops to $1.25/M input and $5.00/M output, and Sonnet 4.5 drops to $1.50/M input and $7.50/M output. GPT-4o stays cheaper in batch mode by the same margin as live mode.